Siemens does not recommend using a virtual machine (VM) with MSIB when leveraging features that require the License Utility Manager (LMU). Non-licensed features such as the Navigator or Data Center Hub service are not affected by this.

If you use a VM environment with MSIB and you select a service requiring a license, you must install two instances of the License Manager Utility (LMU) – physical machine and VM. You must install the license on the physical machine and then point the VM LMU to the physical machine in order for VM MSIB to be functional. 

See the section titled Applying Certificate and Key Files for information concerning HTTPS auto-generated, self-signed certificates and key files.